Tutorial: Electroporation of cells in complex materials and tissue

Articles you may be interested in Simultaneous chemical and electrical stimulation on lung cancer cells using a multichannel-dual-electric-field chip Tuning nano electric field to affect restrictive membrane area on localized single cell nano-electroporation Appl. Model study of electroporation effects on the dielectrophoretic response of spheroidal cells Electroporation is being successfully used in biology, medicine, food processing, and biotechnology, and in some environmental applications. Recent applications also include in addition to classical electroporation, where cells are exposed to micro-or milliseconds long pulses, exposures to extremely short nanosecond pulses, i.e., high-frequency electroporation. Electric pulses are applied to cells in different structural configurations ranging from suspended cells to cells in tissues. Understanding electro-poration of cells in tissues and other complex environments is a key to its successful use and optimization in various applications. Thus, explanation will be provided theoretically/numerically with relation to experimental observations by scaling our understanding of electroporation from the molecular level of the cell membrane up to the tissue level. Published by AIP Publishing.